Seeing Is Believing How The Mip-Luc Mouse Can Advance The Field Of Islet Transplantation And Beta-Cell Regeneration

In the last five years, bioluminescence has emerged as a vital tool in the non-invasive quantification of beta-cell mass following islet transplantation in murine models. The successes achieved in bioluminescence imaging in islet transplantation has prompted its use in the discipline of beta-cell regeneration. Employing bioluminescence permits quantifying changes in beta-cell mass in an individual mouse over time, which can provide valuable insights into the kinetics of beta-cell regeneration.