Intravenous Loop Diuretics and Renal Outcomes in Patients Hospitalized with Acute Decompensated Heart Failure: Insights from the ADHERE Registry

Tabled 1Outcomes vs Loop Diuretic DosingOutcomesHigh vs Low dose propensity & risk adjusted OR (95% CI) of outcomeP valueSCr increase > 0.5 mg/dL1.45 (1.33–1.58)< 0.0001≥ 10 mL/min GFR decline1.63 (1.52–1.75)< 0.0001Initiation of dialysis1.45 (1.20–1.76)0.0001Length of stay > 4 days1.19 (1.15–1.23)< 0.0001ICU admission1.26 (1.19–1.33)< 0.0001ICU LOS > 3 days1.10 (0.98–1.23)0.19In hospital mortality1.16 (1.04–1.30)0.009 Open table in a new tab