维生素E珍珠霜的研制及质量控制
China Pharmaceuticals(2007)
Abstract
目的研制维生素E珍珠霜乳膏并测定其中维生素E的含量。方法以维生素E为主要原料制成乳膏,采用二阶导数光谱法,以维生素E吸收波长295 nm谷峰处的振幅D值作为定量分析信息。结果维生素E质量浓度在60.36~140.84μg/mL范围内与振幅值线性关系良好,方法平均回收率为99.2%,RSD=0.58%。结论制剂处方及制备工艺合理,二阶导数光谱法重现性好,适于该制剂的质量控制。
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Key words
pearl and vitamin E cream,content determination,preparation,second derivative spectrometry
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