The Role Of The Steatosis Of The Donor Graft On Histological Features After Liver Transplantation (Lt)

mortality in non-ALD patients, a subgroup with an observed 5-year survival of more than 80%.Results: Alcoholic liver disease (ALD) alone occurred in 31%, ALD + HCV: 13.7%, HC%' alone: 21.7% and other liver diseases: 33.5%.The median age was 48 years in all groups.88% were Caucasian and 55% were males.Liver transplantation was performed in 292 (18%).Hepamma was diagnosed in 37 (2.3%).Universal risk factors for mortality were, male gender: Hazard ratio (HR) 1.7, 95% C.L 1.3-2.2,age: HR 1.04, 95% C.I. 1.02-1.05,MELD score: HR 1.8, 95% C.I. 1.6-2.1, and active tobacco use: HR 1.4, 95% C.I. 1.1-1.9.Continued alcohol abuse after diagnosis predicted mortality in ALD patients (HR 1.9, 9% C.1.1.1-3.1).Etiology, of liver disease was not a significant predictor of mortality after adjusting tot liver disease severity at presentation.The median MELD score was 8 (range -10 to 55), MELD scores at presentation were ALD: 13, ALD+ HCV: 8, HCV: 4, all others: 7.In all there were 102 deaths at 3 months and 167 at 1 year.Tbe concordance between actual and predicted 3-month mortality using MELD was 0.89 tor all bver patients and for 1-year mortality 0.79.In the non-alcoholic cohorL 61 deaths were observed by I year and the concordance was 0.83.Conclusion: MELD predicts lx, th 3-and 12-month mortality, in a large hospital-based cohort of liver patients, irrespective of disease etiology.It is a good predictor of 1-year mortality in a less severe chronic liver disease group.ALD is a prevalent cause of severe liver disease, with excess mortality attributable to more advanced liver disease at first presentation 12 Hepatic Steatosis on Ultrasound: