还原型谷胱甘肽合复方丹参针治疗酒精性肝病
Zhejiang Journal of Integrated Traditional Chinese and Western Medicine(2006)
Abstract
目的:研究还原型谷胱甘肽联合复方丹参注射液治疗酒精性肝病临床疗效.方法:选择酒精性肝病住院及门诊患者82例,随机分治疗和对照两组,各41例.两组均常规给予门冬氨酸钾镁、维生素类及氨基酸等药物治疗,并严格禁酒.治疗组在此基础上给予还原型谷胱甘肽联合复方丹参注射液治疗,疗程1个月,观察患者症状改善,肝功能指标及影像学变化情况.结果:治疗组总有效率97.6%,对照组63.4%,两组比较,P<0.01;治疗组显效疗程10.6天,明显少于对照组的22.6天,P<0.01.1个疗程结束后,治疗组ALT、AST、GGT、TG、TC下降幅度明显高于对照组,P均<0.01;治疗组ALT、AST、GGT、TG、TC复常率分别为95.1%、90.2%、85.4%、82.9%和80.5%,与对照组比较,P均<0.01.结论:还原型谷胱甘肽联合复方丹参注射液治疗酒精性肝病疗效较好,值得临床推广应用.
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alcoholic liver disease reduced glutathione Fufangdanshen
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