Enalapril versus digoxin in patients with congestive heart failure: A multicenter study

Patients with New York Heart Association functional class II or III heart failure stabilized on furosemide therapy were entered into a randomized controlled trial comparing enalapril (n = 72) and digoxin (n = 73). End points were clinical outcome, treadmill exercise capacity and echocardiographic left ventricular dimensions. Improvement in clinical outcome was defined as a reduction of at least one functional class, and deterioration as an increase of at least one functional class or withdrawal because of an adverse clinical event.