Synthesis and neuroleptic activity of some trans-(2-aminomethyl)-cyclopentyl aryl ketones

European Journal of Medicinal Chemistry(1987)

引用 3|浏览1
暂无评分
摘要
This article describes the synthesis of a series of butyrophenone analogues in which the propyl chain is partially included in a cyclopentane ring. These trans-(2-aminomethyl)cyclopentyl aryl ketones are obtained by reacting (2-bromomethyl)cyclopentyl phenyl ketone or (2-bromomethyl)cyclopentyl p-fluorophenyl ketone with the corresponding heterocyclic amine. The potential neuroleptic activity of these compounds is reported.
更多
查看译文
关键词
butyrophenone analogues,trans-(2-aminomethyl)cyclohexyl aryl ketones,neuroleptic activity
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要