Basic and clinical aspects of BOTOX®

Toxicon(2009)

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摘要
BOTOX® is a botulinum toxin type A product from Allergan that is approved in more than 70 countries, where it addresses unmet patient needs across a variety of indications. BOTOX® is a well-characterized and highly purified biological product that is not interchangeable with any other botulinum neurotoxin. The pharmacology, efficacy and safety profile of BOTOX® has been established in numerous preclinical and clinical studies in addition to meta-analyses. BOTOX® exhibits a predictable response, with a concomitant low rate of neutralizing antibody formation. Allergan is committed to the development of new indications and novel biologics that are designed to benefit individuals with unmet medical needs.
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关键词
Botulinum,Botulinum neurotoxin complex,SNAP-25,Neutralizing antibodies,Dysphagia,BOTOX
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