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锌指蛋白A20在恶性肿瘤中相关研究进展

Chinese Clinical Oncology(2018)

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Abstract
锌指蛋白A20,又称肿瘤坏死因子α诱导蛋白3,它调控多种信号通路参与细胞凋亡和炎症反应等多种生命过程.近年来,A20对多种类型的肿瘤的影响作用日益受到关注.本文旨在从A20的生物学效应以及在肿瘤中发挥致癌作用、抑癌作用、肿瘤耐药性和肿瘤血管形成能力方面做一简要概述.
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Key words
Apoptosis,Zinc-finger protein A20,Tumor,TNFAIP3
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