S-100 Protein In Guinea-Pig Brain During Prenatal Development

Nervous tissue-specific S-100 protein was quantified immunologically in maturing cerebrum, cerebellum and brain stem of guinea pigs during prenatal development. It was found to accumulate in its membrane-bound (pentanol-extractable) form concomitant with the accumulation of the water-soluble S-100 during development, indicating an ability of membranous structures to incorporate S-100 already during development.