冠心病病人血浆细胞黏附分子-1水平的变化
Medical Journal of Qilu（2006）
Abstract
目的 观察冠心病(CHD)病人血浆细胞间黏附分子-1水平的变化,并探讨其与冠心病活动性之间的关系.方法 采用酶联免疫吸附(ELISA)法,检测了60例CHD病人血浆可溶性细胞间黏附分子-1(sICAM-1)的水平,并与健康对照组进行比较.结果 CHD病人血浆sICAM-1水平高于对照组(t=7.136,P＜0.01);且急性心肌梗死(AMI)病人显著高于陈旧性心肌梗死病人及稳定型心绞痛(SA)病人(t=4.329、5.635,P＜0.01),不稳定型心绞痛(UAP)病人高于SA病人(t=3.666,P＜0.01).结论 CHD病人sICAM-1水平明显高于正常对照组,且在一定程度上反映了病情的严重程度.
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Key words
cell adhesion molecules,coronary artery disease,enzyme-linked immunosorbent assay
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