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Influence of various colloidal surfactants on the stability of MS2 bacteriophage suspension. The charge distribution on the PCV2 virus surface

Natalya Vodolazkaya,Anna Laguta,Vladimir Farafonov, Marina Nikolskaya,Zita Balklava,Reza Khayat,Michael Stich,Nikolay Mchedlov-Petrossyan,Dmitry Nerukh

JOURNAL OF MOLECULAR LIQUIDS（2023）

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Abstract
•It was shown the effect of inorganic electrolytes and surfactants on MS2 aggregation, dispersion, and capsid disassembly.•The hydrodynamic diameter and the ζ-potential of PCV2 empty capsid were measured to be 22 ± 1 nm and −41 ± 4 mV respectively.•The local Ψ potential of the PCV2 surface indicates the ‘mosaic’ way of the charge distribution on the capsid surface.
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Key words
MS2 bacteriophage,PCV2 capsid,Hydrodynamic diameter,Zeta-potential,Surface electrostatic potential,Charge distribution on capsid surface
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