Resistance Mutations In Subtype Chiv Type 1 Isolates From Indian Patients Of Mumbai Receiving Nrtis Plus Nnrtis And Experiencing A Treatment Failure: Resistance To Ar

AIDS Research and Human Retroviruses(2007)

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摘要
We present here the first data available on resistance to nucleoside reverse transcriptase inhibitors (NRTIs) and nonnucleoside reverse transcriptase inhibitors (NNRTIs) in India. In these subtype C isolates, we have observed most of the mutations noted in reverse transcriptase (RT) for subtype B with some additional substitutions ( at positions 98, 203, 208, and 221) that will warrant attention in the algorithms used.
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关键词
resistance mutations,hiv,indian patients,nnrtis
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