γ干扰素抗衣原体感染作用的研究进展
Journal of Microbes and Infection(2009)
Abstract
衣原体为专性胞内寄生菌,具有广泛致病谱,是重要的致病菌。γ干扰素在抗衣原体感染中起重要作用,其介导的抗衣原体感染效应机制包括耗竭色氨酸、诱导铁缺失途径以及激活一氧化氮合酶等;但衣原体也有其自身特有的避免γ干扰素干扰的免疫逃避机制。本文综述γ干扰素抗衣原体感染作用机制的研究现状。
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Key words
Immune response,Interferon-γ,Immune escape,Chlamydia
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