Optimization of Matrix Formulation for Geranium wilfordii Cataplasm by Orthogonal Design
Chinese Journal of Experimental Traditional Medical Formulae（2012）
Abstract
Objective:To optimize matrix formulation of Geranium wilfordii cataplasm.Method:With adhesive force,shapability and general sensory as comprehensive evaluation index,ratio of NP700,tartaric acid,PVP-K90 and dihydroxy alumimun aminoacetate were chosen as investigated factors,L9(34) orthogonal experiment was used to evaluate properties of cataplasm with different materials ratio.Result:Optimum matrix formulation of cataplasm was NP700-tartaric acid-PVP K90-dihydroxy alumimun aminoacetate 7.5 ∶ 0.4 ∶ 3 ∶ 0.05.Conclusion:This optimized formulation was feasible and stable with better performance.
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Key words
matrix,cataplasm,Geranium wilfordii,orthogonal experiment
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