A Short Synthesis of an Enantiopure Benzo[e]isoindolinone

Mark D. Andrews,Andrew G. Brewster,John Chuhan,Ashley J. Ibbett,Mark G. Moloney,Keith Prout,David Watkin

SYNTHESIS-STUTTGART（1997）

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摘要

An enantiopure benzo[e]isoindolinone is available by a sequence involving the reaction of a phenyl substituted tetramic acid with two equivalents of a stabilised phosphorane Ph(3)P=CHCO(2)R (R = Et or t-Bu).

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关键词

tetramic acid,benzo[e]isoindolinone,synthesis,Wittig,Dieckmann

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