CD26与ADA结合活化肾癌细胞内TGF-β调控肾癌细胞迁移能力的研究
Journal of Mudanjiang Medical University(2013)
Abstract
目的:探讨CD26与腺苷酸脱氨酶(ADA)结合活化肾癌细胞内TGF-β调控肾癌细胞迁移能力的研究。方法:采用分子生物学的方法检测CD26与ADA结合活化对肾癌细胞迁移能力的影响。结果:外源性对肾癌细胞迁移能力无影响,CD26与ADA结合活化可上调肾癌细胞内TGF-β的表达。结论:CD26和ADA结合后上调TGF-β在调控肾癌胞迁移性能力中发挥重要作用。
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Key words
renal carcinoma,Molecular Biology,CD 26,migration ability,ADA
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