单唾液酸四己糖神经节苷脂钠早期治疗新生儿缺氧缺血性脑病的临床疗效
Journal of Bengbu Medical College(2013)
Abstract
目的:观察单唾液酸四己糖神经节苷脂钠早期治疗新生儿缺氧缺血性脑病的临床疗效。方法:将62例缺氧缺血性脑病患儿随机分成治疗组32例和对照组30例,对照组采用常规治疗,治疗组在常规治疗基础上于出生后24 h加用单唾液酸四己糖神经节苷脂钠20 mg静脉滴注,每天1次,10~14 d为1疗程。比较2组患儿临床症状体征恢复及新生儿行为神经评分。结果:治疗组临床症状体征的恢复及新生儿行为神经评分均优于对照组(P<0.01)。结论:早期应用单唾液酸四己糖神经节苷脂钠治疗新生儿缺氧缺血性脑病有明显疗效,未见不良反应发生。
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Key words
Neonatal behavioral neurological assessment,Hypoxic—ischemic encephalopathy,Newborns,Ganglioside,ganglioside,neonatal behavioral neurological assessment,hypoxic-ischemic encephalopathy
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