Investigations on endocrine responses in the bitch following hysterectomy

R. HOVELER, P. EVERS, B. HOFFMANN

European Journal of Endocrinology(1987)

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Abstract
In most domestic species (e.g. cattle, sheep) prostaglandin F2α of endometrial origin is considered to be the active principle leading to luteolysis at the end of the estrous cycle; hence in these species hysterectomy leads to the formation of a persistent corpus luteum, the application of PgF2α induces luteolysis. Data for the bitch are conflicting; while exogenous application of PgF2α or analog acting compounds can lead to a decline in peripheral plasma progesterone levels [1], hysterectomy during the on-going cycle apparently does not lead to early luteal regression [2]. In order to obtain further information, a long-term study was designed of hysterectomized bitches and an equal number of control animals.
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Key words
endocrine responses,bitch
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