ChemInform Abstract: Synthesis, Characterization, and in vitro Anthelmintic Activity Against Nippostrongylus brasiliensis of New 5-Aryl-2-phenyl-6,7-dihydropyrazolo[1,5-a]pyrimidines.

Several new pyrazolo[1,5-a]pyrimidines were obtained from the reaction of 1H-5-amino-3-phenylpyrazole (1) with β-dimethylaminopropiophenones 2 in pyridine. The structure elucidation of 6,7-dihydropyrazolo[1,5-a]pyrimidines 3 is based on nmr measurements. These compounds showed moderate anthelmintic in vitro activity against the Nipposirongylus brasiliensis model.