Developing fixed-parameter algorithms to solve combinatorially explosive biological problems.

Methods in molecular biology (Clifton, N.J.)(2008)

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摘要
Fixed-parameter algorithms can efficiently find optimal solutions to some computationally hard (NP-hard) problems. This chapter surveys five main practical techniques to develop such algorithms. Each technique is circumstantiated by case studies of applications to biological problems. It also presents other known bioinformatics-related applications and gives pointers to experimental results.
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关键词
computationally hard problems,discrete problems,combinatorial explosions,optimal solutions.,fixed-parameter tractability
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