注射用盐酸头孢甲肟治疗急性细菌感染的临床评价
PROGRESS IN PHARMACEUTICAL SCIENCES(2008)
Abstract
目的:考察注射用盐酸头孢甲肟治疗急性细菌感染的临床疗效、细菌学疗效和安全性.方法:将126名入选患者随机分为两组:试验组(n=62)和对照组(n=64),分别接受同剂量注射用盐酸头孢甲肟和头孢噻肟钠静脉滴注治疗(2 g,bid),疗程为7~14 d.结果:试验组和对照组的临床痊愈率分别为74.19%和68.75%(P=0.8844),有效率分别为95.16%和95.31%(P=0.9020),均无显著差异;两组细菌清除率分别为90.57%和86.54%(P>0.05),无显著差异;两组不良反应发生率分别为1.61%和4.69%(P>0.05),无显著差异,且不良反应大多轻微并为一过性.结论:注射用盐酸头孢甲肟可安全、有效地用于治疗急性细菌感染.
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Key words
injectable cefmenoxime hydrochloride,infection,treatment,acute,clinical
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