Bitungolides A−F, New Polyketides from the Indonesian SpongeTheonellacf.swinhoei

Sodngam Sirirath,Junichi Tanaka,Ikuko I. Ohtani,Toshio Ichiba,Rachmaniar Rachmat,Kazunori Ueda,Takeo Usui,Hiroyuki Osada,Tatsuo Higa

JOURNAL OF NATURAL PRODUCTS（2002）

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摘要

Six new polyketides, bitungolides A-F (1-6), have been isolated from the Indonesian sponge Theonella cf swinhoei and their structures elucidated by spectroscopic data and X-ray diffraction analysis. The bitungolides are a new class of Theonella metabolites that inhibit dual-specificity phosphatase VHR.

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new polyketides

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