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回、汉族冠心病与血管紧张素转换酶基因多态性的相关性研究

LIU Hui

Ningxia Medical Journal（2008）

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Abstract
目的探讨血管紧张素转换酶基因插入/缺失多态性与宁夏回、汉族冠心病的相关性。方法运用聚合酶链反应技术对宁夏90例回族(冠心病组、对照组各45例)、80例汉族(冠心病组、对照组各40例)进行血管紧张素转换酶基因多态性检测,并进行分析比较。结果回族冠心病组DD基因型高于回族对照组(P<0.05),汉族冠心病组和对照组ACE基因型分布比较未出现统计学意义(P>0.05)。结论血管紧张素转换酶基因I/D多态性与回族冠心病存在一定关系。
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Key words
Han ethnic,Polymorphism,Angiotensin-converting enzyme(ACE)gene,Coronary heart disease,Hui ethnic
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