Sonografisch gezielte Stanzbiopsie: 15 Jahre Follow-up

Purpose: Between 5/1992 and 4/1993, we performed 307 ultrasound-guided core cut biopsies. In 119 of these 307 women, we dispensed with any further surgical and histological procedures when the tentative diagnosis based on complementary mammary diagnostic procedures revealed no pathological findings and concurred with the histological results of the core cut biopsy. Aim of our study was a follow-up after 15 years. Materials and Methods: We performed ultrasound-guided core cut biopsies (7.5 mHz array; core cut biopsy systems from the manufacturers BIP (TM), today BARD Angiomed T and Pflugbeil T; coaxial and core cut needles with a length of 10 cm, a diameter of 2.1 mm (14 G); core cut depth 1.6 or 2.2 cm; 1-3 specimens) in 119 women with a benign histology. The control intervals were 3, 6, 12 and 24 months for sonographic controls, mammography at 12 and 24 months and a follow-up after 15 years. Results: It was possible to perform a follow-up in 103 of 118 patients. In one patient, a histologically verified fibroadenoma with a tendency to growth was operated and its benign histology was confirmed. A second patient underwent therapy for a lobular carcinoma at 43 months after core cut biopsy with the histology "simple mastopathy". The third patient was operated on for breast cancer at 56 months after intervention in an area where the result of the core cut biopsy had been "too little material available". The sensitivity, specificity, ppV and npV was 98% in each case (p < 0.0001). Conclusion: Precondition for the feasibility of ultrasound-guided core cut biopsies is the consistent application of the S3 guidelines.