Effects of chronic β-carotene supplementation on vitamin K status in adults
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL(2009)
Abstract
Plasma vitamin K concentrations and prothrombin coagulation activity were determined in 26 normal adults who had received daily beta-carotene supplementation (0, 15, 30, or 60 mg) for six months. Neither plasma vitamin K nor coagulation activity were significantly decreased at any supplementation level. Thus, chronic beta-carotene supplementation, even at high daily doses, is not expected to result in clinical vitamin K deficiency. The data suggest separate mechanisms for intestinal absorption of beta-carotene and vitamin K.
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Key words
chronic<i>β</i>‐carotene,vitamin
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