Structure stability/activity relationships of sulfone stabilized N,N-dichloroamines.

Eddy Low,Bum Kim,Charles Francavilla,Timothy P Shiau,Eric D Turtle,Donogh J R O'Mahony,Nichole Alvarez,Ashley Houchin,Ping Xu,Meghan Zuck,Chris Celeri,Mark B Anderson,Ramin Ron Najafi,Rakesh K Jain

Bioorganic & Medicinal Chemistry Letters（2011）

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摘要

This study identified a new class of solution-stable, topical, antimicrobial agents. These agents are sulfone-stabilized and possess either a quaternary ammonium or sulfonate as a water solubilizing group.

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Antimicrobial,N-Chloroamine

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