Enzymatic Method of Preparation of Opticallly Active Trans-2-Amtno Cyclohexanol Derivatives
SYNTHETIC COMMUNICATIONS(2007)
摘要
Supported Lipase Amano PS-D catalyzes the resolution of (+/-)-trans-2-tert butoxycarbonyl amino cyclohexanol by a selective acylation reaction Using the supported enzyme gave a much faster reaction compared to existing methodology on similar substrates. A variety of acylating agents were investigated, with vinyl acetate providing the most practical and convenient procedure.
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关键词
enzyme
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