Physiological Role Of Type Ii Bone Morphogenetic Protein Receptor And Its Interacting Molecules In Bone Morphogenetic Protein Signaling
INTERFACE ORAL HEALTH SCIENCE 2009(2010)
Abstract
Type II bone morphogenetic protein (BMP) receptor (BMPRII) is a membrane receptor containing a unique tail domain. This kinase receptor is involved in various biological processes, including bone formation. Recent studies have revealed that novel BMPRII-interacting proteins are involved in the Smad signaling pathway or in the non-Smad signaling pathway. This report focuses on BMPRII-mediated signal transduction and provides advanced insights into the physiological roles of BMPRII.
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Key words
bone morphogenetic protein (BMP), BMP receptor
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