Chondroblastoma in foot:a clinicopathologic analysis of five cases

Purpose To investigate the clinicopathological and immunohistochemical features and imaging changes as well as the prognosis of chondroblastoma in the foot.Methods The literatures related to chondroblastoma in the foot in recent years were reviewed and five cases were reported.Meanwhile,the diagnosis and differential diagnosis,clinicopathological and immunohistochemical features as well as image changes were analyzed.Results Radiologic features showed an osteolytic lesion.Histologic feature of chondroblastoma included sheets of closely packed roundish or polygonal chondroblastic cells with interspersed multinucleated giant cells and islands of hypocellular eosinophilic cartilage matrix,focal areas of dystrophic calcification,and S-100(+).Conclusion The chondroblastoma occurred in the foot is rare and its estimated incidence is about 13% in chondroblastoma.The tumor is rare and its diagnosis must be combined the clinical,pathologic features with its image changes.