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从肝论治法对白癜风β-EP、CGRP、NPY表达的影响

Journal of Youjiang Medical University for Nationalities(2013)

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Abstract
目的观察从肝论治法治疗寻常型白癜风的临床效果。方法将符合标准的寻常型白癜风患者分为治疗组35例与对照组35例,两组患者均经过2周洗脱期后,治疗组口服复方祛白颗粒,同时外用复方祛白酊治疗。对照组口服白癜风胶囊,同时外用复方祛白酊。治疗3个月后,检测寻常型白癜风患者血浆β-内啡肽(beta-Endorphin,β-EP)、降钙素基因相关肽(calcitonin gene-related peptide,CGRP)、神经肽Y(neuropeptide Y,NPY)水平。结果与对照组相比,治疗组疗效明显优于对照组(P<0.05)。与对照组相比,治疗组β-EP、CGRP、NPY水平明显低于对照组(P<0.05)。结论从肝论治法治疗寻常型白癜风具有较好的临床疗效,β-EP、CGRP、NPY水平的升高很可能是寻常型白癜风发病的重要因素。
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Key words
vitiligo,calcitonin gene-related peptide,beta-Endorphin,Theory of Treatment from Liver,neuropeptide Y
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