Potential use of microencapsulation for sustained drug delivery to the respiratory tract.
JOURNAL OF AEROSOL MEDICINE-DEPOSITION CLEARANCE AND EFFECTS IN THE LUNG(2009)
Abstract
Microencapsulation has long been regarded as a means of achieving sustained drug delivery. In these studies, a spray drying technique was used to produce salbutamol-loaded albumin microparticles with a view to formulating a controlled release system to be used in respiratory drug delivery. Encapsulation efficiencies (40-60 % w/w) obtained using this technique compared very favourably with those obtained using emulsification procedures (1-2 % w/w).
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Key words
microencapsulation,sustained drug delivery,respiratory tract
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