Stereoselective synthesis of gem-dimethyl-5,5-pyrrolidine-trans-lactam (5-oxo-hexahydropyrrolo[3,2-b]pyrrole)
Tetrahedron Letters（2001）
摘要
The gem-dimethyl-trans-lactam 6 could be prepared by alkylation of the β-methyl isomer 7 but not by alkylation of the α-isomer 5.
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关键词
stereoselective alkylation,5,5-trans-lactam ring pyrrolidines/pyrrolidinones
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