Reflectance confocal microscopy for melanoma and melanocytic lesion assessment

Reflectance confocal microscopy (RCM) is an emerging noninvasive diagnostic tool that provides in vivo tissue images at nearly cellular histological resolution. Peculiar confocal findings of melanocytic lesions have been evaluated and applied in real clinical settings to elucidate the impact of RCM in improving diagnostic accuracy. This review aims to clearly update the relevant confocal findings and to critically analyze their role in the clinical scenario.