Dihydropyrazolopyrimidine Inhibitors of KV1.5 (IKur)
Bioorganic & Medicinal Chemistry Letters（2008）
Abstract
A series of dihydropyrazolopryimidine inhibitors of KV1.5 (IKur) have been identified. The synthesis, structure–activity relationships and selectivity against several other ion channels are described.
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Key words
Dihydropyrazolopyrimidine,KV1.5,IKur,Ion channels,Potassium channel,Atrial fibrillation
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