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自发性细菌性腹膜炎患者腹水LPS、IL-6、PCT测定的临床意义

Zhejiang Medical Education(2009)

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Abstract
目的:探讨肝炎肝硬化并发自发性细菌性腹膜炎(SBP)患者腹水中内毒素(LPS)、白细胞介素-6(IL-6)、降钙素原(PCT)水平的变化及其临床意义。方法:183例肝炎肝硬化并发腹水患者作腹水LPS、IL-6和PCT水平检测,所有SBP患者腹水均作细菌培养。结果:97例SBP患者腹水LPS、IL-6、PCT水平明显高于86例无SBP患者(P<0.01),G-菌SBP腹水中的1PS水平明显高于G~+菌SBP腹水(P<0.01)。结论:腹水LPS、IL-6、PCT水平的检测有助于SBP的诊断,并且腹水LPS水平的检测还有助于SBP病原菌的鉴别。
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Key words
endotoxin,liver cinfaosis,Interleukin-6,procalcitonin,spontaneous bacterial peritonitis
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