The Involvement of Hippocampus and Amygdala in Schizophrenia

Amygdala lesions result in emotional deficits, such as facial affect recognition, that occurs also in schizophrenic patients, especially paranoid, compared to non-paranoid. The volume of amygdala may be inversely correlated with the number of X chromosomes. Hippocampus lesions can produce symptoms that resemble both the positive and the negative symptoms of schizophrenia. However those volume reductions are not specific findings of schizophrenia, since they are also found in bipolar patients and even in normal elderly persons.