Loss of heterozygosity analysis in uterine cervical adenocarcinoma

Kentaro Miyai,Yoshiaki Furugen,Toshiharu Matsumoto,Keiichi Iwabuchi,Sachiko Hirose,Katsuyuki Kinoshita,Hiroaki Fujii

Gynecologic Oncology（2004）

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摘要

Objective. Uterine cervical adenocarcinoma (CAC) is a rare form of cervical cancer, constituting only 5–8% of all cervical epithelial malignancies. Loss of heterozygosity (LOH) analysis of CAC was undertaken to identify alterations of chromosomal loci that may play important roles in the development of this tumor type.

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关键词

Loss of heterozygosity,Cervical adenocarcinoma,Microsatellite,Tumor suppressor gene,Cervical carcinoma

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