P01-230 Activation of serotonin metabolism and BDNF changes in depressed patients with multiple sclerosis during interferon-beta therapy

S. Bonaccorso,A. Ricciardi,F. Matrisciano,F. Nicoletti,S. Scaccianoce,A. Ruberto,P. Girardi,R. Tatarelli,F. Pompei,R. Manciocchi,C. Pozzilli,R. Verkerk,S. Scharpe,L. Wang, R. Shelton

European Psychiatry（2009）

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摘要

Discussion The increase in HAA among the psychotherapy-treated patients raises the possibility of a neurodegenerative challenge for patients with multiple sclerosis during treatment with IFN-β which appeared to be prevented with pharmacological treatment.

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multiple sclerosis,serotonin metabolism,depressed patients,bdnf changes,interferon-beta

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