ERβ ligands. Part 5: Synthesis and structure–activity relationships of a series of 4′-hydroxyphenyl-aryl-carbaldehyde oxime derivatives

Richard E. Mewshaw,S. Marc Bowen,Heather A. Harris,Zhang B. Xu,Eric S. Manas,Stephen T. Cohn

Bioorganic & Medicinal Chemistry Letters（2007）

引用 24|浏览9

暂无评分

摘要

A series of 4′-hydroxyphenyl-aryl-carbaldehyde oximes (5b) was prepared and found to have high-affinity (4nM) and modest selectivity (39-fold) for estrogen receptor-β.

查看译文

关键词

Estrogen receptor ligands,Oximes

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要