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多肿瘤标志物蛋白芯片检测糖链抗原125的临床价值分析

Journal of Modern Oncology(2007)

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Abstract
目的研究糖链抗原125升高在恶性肿瘤及良性疾病中的意义。方法应用蛋白芯片法检测253例不同种类恶性肿瘤及良性疾病标本。结果CA125在卵巢癌、肺癌、肝癌、胰腺癌、子宫癌、结/直肠癌的阳性率依次为68.7%、66.6%、57.7%、50%、46.6%、42.8%,总阳性率是59.6%;肝硬化的阳性率达78.9%。结论CA125不只是卵巢癌的指标,也是一种广谱肿瘤标志物,并且肝硬化等良性疾病也有较高的阳性率,可作为健康体检中筛选异常人群的指标。
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Key words
carbohydrate antigen 125,tumor,protein biochip
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