复方桑参米诺地尔搽剂中米诺地尔的HPLCLC定
Chinese Journal of Pharmaceuticals(2007)
Abstract
建立了高效液相色谱法测定复方桑参米诺地尔搽剂中米诺地尔的含量.采用C18柱,流动相为甲醇-乙腈-水(40:10:50),流速1.2ml/min,检测波长230nm,内标为对乙酰氨基酚.米诺地尔在3.6~9.6μg/ml浓度范围内线性关系良好(r=0.9999),回收率大于98%,日内和日间RSD均小于1%.
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Key words
HPLC,minoxidil,compound Sangshen minoxidil liniment,determination
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