肿节风的有效部位对小鼠继发性血小板减少症的药效学研究

Information on Traditional Chinese Medicine(2013)

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Abstract
目的:建立阿糖胞苷诱发小鼠血小板减少模型,研究肿节风及其各分离部位对继发性血小板减少性紫癜小鼠的作用,找出肿节风的有效作用部位.方法:ICR小鼠注射阿糖胞苷造成血小板减少的模型,同时灌胃给药肿节风及其各分离部位,观察肿节风及其各分离部位的小鼠的外周血象变化.结果:肿节风组及其总黄酮组有明显提升血小板的作用.结论:肿节风有抗继发性血小板减少性紫癜的作用,其分离部位总黄酮部位为其抗继发性血小板减少性紫癜的有效部位.
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Key words
Sarcandra glabra,Sequenced Thrombocytopenic Purpura,Active fraction,Cytarabine
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