Relationship between a validated molecular cardiac transplant rejection classifier and routine organ function parameters.

Martin Cadeiras,Khurram Shahzad, Manju M John,Dorota Gruber,Manuel von Bayern,Scott Auerbach,Anshu Sinha,Farhana Latif,Sreevalsa Unniachan,Sarfaraz Memon,Seema Mital,Susan Restaino,Charles C Marboe,Linda J Addonizio,Mario C Deng

Clinical transplantation（2010）

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摘要

A GEP test developed and validated to detect the absence of cardiac rejection correlates with electrocardiographic and hemodynamic cardiac parameters as well as renal, hepatic, bone marrow, and lipid metabolism parameters suggesting a complex relationship between rejection, leukocytes, and organ function within the continuum between alloimmunological quiescence and rejection.

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关键词

electrocardiography,gene expression,heart transplantation,hemodynamics,molecular testing

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