Heart rate variability analysis in patients with a stable coronary heart disease. Analysis using novel methods in combined time-frequency domains

Journal of Electrocardiology(2007)

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摘要
Evaluar los efectos de un programa recreativo de actividad física general, de intensidad moderada y corta duración, sobre las cifras de hipertensión arterial y otros factores de riesgo cardiovascular (FRCV) en hipertensos mayores de 50 años.Estudio cuasi-experimental no aleatorizado con diseño pre-post.Íllora (Granada).Sesenta sujetos sedentarios de 50-75 años pertenecientes al programa de hipertensos del Centro de Salud.Programa lúdico de actividad física general donde predomina la capacidad aeróbica, 3 días/semana, durante 4 semanas, y una intensidad del 45-55% de la FC Reserva.PAS, PAD, FC, IMC, colesterol total, HDL, LDL, TG y glucosa.Disminuciones estadísticamente significativas (p < 0,05) en el IMC (−0,51%; IC 95%: 30,26-31,93 unid), la FC (−5,57 lat/min; IC 95%: 68,76-71,73 lat/min), la PAS (−14,82 mmHg; IC 95%: 131,57-137,52 mmHg), la PAD (−5,33 mmHg; IC 95%: 78,94-83,68 mmHg), la glucosa (−7,63 mg/dl; IC 95%: 125,06-153,73 mg/dl) y el riesgo REGICOR (−20,46%; IC 95%: 5,45-6,90%).Aumentos estadísticamente significativos en el HDL (+2,82 mg/dl; IC 95%: 46,78-52,11 mg/dl) y los TG (+8,27 mg/dl; IC 95% 133,89-152,60 mg/dl).Según el sexo, los hombres presentaron la mayor variación en la FC y la PAD, y las mujeres en la PAS (p < 0,05). Sujetos con valores iniciales de PAS ≥ 160 mmHg experimentaron mayores descensos de FC, PAS, PAD, glucosa y TG (−10,67 lat/min, −31 mmHg, −8,27 mmHg, −10,86 mg/dl y 34,66 mg/dl, respectivamente) que aquellos con PAS inicial < 160 mmHg, donde aumentó el HDL y disminuyó el LDL.Tras este programa se obtuvieron mejoras en la presión arterial y otros FRCV en sujetos hipertensos mayores de 50 años.To evaluate the effects of a recreational general physical activity program with moderate intensity and short duration on blood pressure and other cardiovascular risk factors (BMI, cholesterol, Rest Heart Rate, HDL, LDL, Triglycerides) in hypertensive patients older than 50 years.Non-randomised pre-post design, quasi-experimental study.Íllora, Granada, Spain.A total of 60 subjects aged 50-75 years taking part in the Health Hypertensive Program in the Medical Centre were selected.A recreational general physical activity program, mainly aerobic capacity, of 4 weeks duration, 3 days/week, and an intensity of 45-55% HR Reserve.SBP, DBP, HR, BMI, total cholesterol, HDL, LDL, TG, and Glucose.Statistically significant decreases (P < .05) were observed in BMI (−0.51%; 95% CI: 30.26 to 31.93 units), HR (−5.57 beats/min; 95% CI: 68.76 to 71.73 beats/min), SBP (−14.82 mmHg; 95% CI: 131.57 to 137.52 mmHg), DBP (−5.33 mmHg; 95% CI: 78.94 to 83.68 mmHg), Glucose (−7.63 mg/dL; 95% CI: 125.06 to 153.73 mg/dL) and REGICOR risk (−20.46%; 95% CI: 5.45 to 6.90%).Statistically significant increases were observed in HDL (+2.82 mg/dl; 95% CI: 46.78 to 52.11 mmHg), and TG (+8.27 mg/dl; 95% CI: 133.89 to 152.60 mg/dL).Men had a wider variation in HR and DBP, and women in SBP (P < .05). Subjects with baseline SBP ≥ 160 mmHg experienced greater declines in HR, SBP, DBP, Glucose and TG (−10.67 beats/min, −31 mmHg, −8.27 mmHg, −10.86 mg/dL, and 34.66 mg/dL, respectively) than those with an initial SBP < 160 mmHg, where there was an increase in HDL and a decrease in LDL.After this program, improvements in BP and other cardiovascular risk factors were obtained in hypertensive subjects over 50 years.
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time frequency,heart rate variability
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