Matrix Gla protein C-terminal region binds to vitronectin. Co-localization suggests binding occurs during tissue development
Matrix Biology(2005)
Abstract
Matrix Gla protein (MGP) regulates calcification in cartilage and arteries. MGP synthesis during embryonic development and its binding and regulation of growth factors and morphogens of the TGF-beta/BMP superfamily suggests that it has additional functions.
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Key words
MGP,SDS,PAGE,kDA
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