Synthesis Of [Phenyl-U-C-14]Aryl And [8-C-14]Carboxy Labeled Tracers Of Vorinostat
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS(2006)
摘要
In support of a program to develop a treatment for advanced, refractory cutaneous T-cell lymphoma, two differentially [C-14]-labeled forms of vorinostat, a histone deacetylase inhibitor, were synthesized for use in metabolism studies. Copyright (c) 2006 John Wiley & Sons, Ltd.
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关键词
CTCL, HDAC, SAHA, suberoylanilide hydroxamic acid, vorinostat
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