脑出血微创清除术应用低温复合冲洗液对血肿周围水肿带的影响
Chinese Journal of Practical Nervous Diseases(2008)
Abstract
目的观察高血压脑出血患者微创术中应用低温复合冲洗液对血肿周围水肿面积及神经功能的影响。方法高血压脑出血患者50例,随机分为治疗组和对照组各25例,治疗组在微创术中应用低温复合冲洗液(冰生理盐水、地塞米松、纳洛酮)冲洗,对照组应用常温生理盐水冲洗,2组均行脑出血的常规治疗,观察2组患者第7、15d与第1d病灶周围水肿面积及神经功能缺损评分之差。结果2组病人术后第1d与第7、15d头颅CT上最大灶周水肿面积之差(治疗组1.02±0.06与1.86±0.12,对照组0.53±0.04与0.61±0.07)及神经功能缺损评分之差(治疗组5.51±1.12与8.24±2.14,对照组2.16±1.32与3.56±1.26)均有显著性差异(P<0.01)。结论低温复合冲洗液能明显减小微创术后病灶周围水肿面积,使神经功能恢复水平进一步提高。
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Key words
Dexamethasone,Mild hypothermia,Micro scar operation,Brain edema,Cerebral hemorrhage,Naloxone
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