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Endogenous endostatin attenuates postinfarction ventricular remodeling by inhibiting matrix metalloproteinase activity

Kazuya Isobe,Yasuhiro Maejima,Mitsuaki Isobe, S. K. Kubota

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY（2007）

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Abstract
Objective: Left ventricular (LV) remodeling is a major cause of progressive heart failure and death after myocardial infarction (MI). The role of endostatin, an antiangiogenic factor, in LV remodeling remains unclear.
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cardiac remodeling,infarction,angiogenesis
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