Wnt信号传导与肿瘤

Oncology Progress(2009)

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Abstract
近年来,随着对肿瘤的深入研究,Wnt信号的研究也受到了很高的关注。Wnt信号传导途径控制胚胎发育,调节细胞生长、迁移和分化,调控正常组织重建及干细胞增殖,其紊乱与众多人类肿瘤的发生密切相关。本文就Wnt信号的传导途径及其与肿瘤发生的关系作一综述。
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Key words
Wnt,neoplasms,signal transduction
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